Let me state outright that the information contained in this blog is complicated, probably very dry, and not what most people will want to wade through. However, the information is important and somewhat uncomfortable, but necessary to be informed.

During the two impeachments of Donald Trump, everyone became a Constitutional legal scholar with a complete understanding of all that is related to the Constitution and law. Then we had the Corona virus and with it we became scientists by osmosis, and everyone was an epidemiologist with a concentration in the field of viruses and retroviruses.

In reality when we look at those with the strongest comments to make on many topics we see the kids we knew in school who hated Social Studies or just about grasped the concepts included in the biology class.

Now we are on the topic of Chromosomes and Transgender people and, just as with the Constitution and Covid 19, having heard about something from someone without that person having done any research beyond a meme and without doing any research ourselves, we proudly pontificate on our intuition-based knowledge.

So, based on a rudimentary understanding of Chromosomes, everyone is now an expert on DNA.

Grasping tightly to their quick explanation of Chromosomes in Biology class, if we paid attention, and having done the dominate and recessive gene charts that showed the chances of what our offspring might be, we are convinced that we know all there is to know except, it isn’t as cut and dry as our high school biology teachers told us because he had to follow the established curriculum. Some idea about chromosomes was important, especially as it could be on a standardized tests to which kids are annually subjected.

We learned that Females had two X shaped chromosomes and males had one X and one Y chromosome. This determined Chromosomal Sex, and that is all we needed to know to pass the test, so that is as far as we got.

When it comes to human gestation things are not as simple as what we were required to learn to cover the curriculum.

Our knowledge of what happens in fertilization and fetal development has changed since Anton van Leeuwenhoek invented the microscope and burgeoning scientist began putting anything translucent they could think of under the lens. When one person decided to look at semen more closely, he found the little tadpole looking things swimming around and the belief grew that while the woman was the empty vessel waiting for the man to fill her womb, the sperm contained a tiny fully formed human that was placed in the female so it would grow.

We know this not to be true as more things were discovered, so our understanding of fertilization, gestation, and birth have had to change with the times, just as now, with more information, we should be willing to look at and discover this new information and give up what, in our limited experience, was all we knew about the process like had to be done when the telescope began discovering other planets and the sun, not the earth, was the center of our little planetary system.

At certain points in fetal development hormones must be released  in order for cells to develop into the various part of us they are supposed to. Going pass the generic and extremely limited knowledge of X/Y Chromosomes it has been found that only one gene on the Y Chromosome (the male one) has any relation to sex, and releases the SRY Protein that initiates the Male sex genes to get moving.

Without that SRY gene on the Y Chromosome and, therefore, with nothing to kick in, the simple wrong assumption is that with the XY the fetus will be male. Not being part of, but attached to the Y chromosome this particular SRY Gene can detach from it and meander over to the X so now the male gene is no longer on the male Y but the female X.

So, what happens when this migration takes place?

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With the SRY Gene no longer where it was supposed to be, a person is physically “female” while being Chromosomally male because a Y without the SRY makes a person physicaly female as the SRY isn’t on the Chromosome that is waiting for the signal to get on with male sexual development that will not arrive as it will be somewhere else doing its thing there. Chromosomaly under these conditions, with the X and Y, the person is genetically male, Physically female ( you need to take into count secondary sexual characteristics that either males and frmales have, or may lack, without any essential change to the person’s reality. I know a male who has never had to shave because the secondary sexual characteristic for males having facial hair did not kick in. Is he less male?), and genetically female.

The X with the SRY attached means a person is physically male because the signal has been sent to wrong place, could be chromosomely female, yet also genetically male.

It is not the Chromosome combo but where the SRY stays or ends up that is important.

As the fetus develops, the sex related hormones send signals to the various cells to develop the correct plumbing as time goes on. At one point all fetuses are female as no sex hormones have yet to be released, and proof of this is in male nipples and that odd seam on the scrotum that is what is left of a possible Vagina if signals had been sent differently or at the wrong time in male and the right in females.

The confusion enters when people assume the visible marks of either male or female are the whole story.

Wrong hormones delivered early, late, or not in the proper amount influence development and may or may not result in someone being physically male while Chromosomally female, and this also deternmines those who are non-binary.

This is complicated because the receptors of the signals must be prepared and able to received the signals , and this can be partial or not at all. All the little bits of the “miracle of Birth and proof of God” must all function properly and at the right time inspite of all that could influence this both from the developing fetus or what the mother is doing with her body.

As much as we might have paid for our smart phone, we still have calls dropped or messages missed and delayed.

With the Chromosomes dealing with a potentially roaming or misattached SRY Gene and other influences like poor or untimely messageas sent and similarly received, a person could be genetically male and female, Chromosomally male and female, hormonally male and female in any combination.

Determining one’s gender or sex is not as simple as just a peek down the pants.

If this layman’s description of the XX/XY/SRY situation was too long, perhaps too boring, or just too confusing to grasp, that is why these people who are making anti-Transgender laws or acting out their rejection of Transgender people to the point of murder need more education unless, having done it, they find it better to just ignore that which does not support their bigotry.

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